Cadwalader Wickersham & Taft is moving to new premises in Bank which will see the firm almost halve its office space in the capital.
The US firm will be housed at Dashwood House at 69 Old Broad Street by December this year.
The move comes after The Lawyer revealed that Cadwalader was considering three different buildings in the City – all three of which would reduce the size of the office in London from around 35,000 sq ft to around 18,000 sq ft (20 July)
After a management meeting last week the firm has opted to lease the 14th and 15th floors of Dashwood House.
The firm took the decision back in February to search for smaller premises. Cadwalader served notice on its office at 265 Strand last year meaning it will have to vacate the building in February 2010.
The office move comes after the firm has suffered a number of defections in the London office.
Earlier this year The Lawyer reported that Cadwalader suffered a seven partner walkout with a team defecting to Paul Hasting Janofsky & Walker (14 January)