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Personal injury powerhouse Thompsons is to take over eight-partner firm Whittles, which has offices in Leeds and Manchester, from the 1 May.
Both firms specialise in personal injury, trade union work and employment rights.
Stephen Cavalier, chief executive of 48-partner firm Thompsons, said the merger builds on both Thompsons' and Whittles' commitment to the trade union movement.
"We are, together, uniquely placed to provide even greater strength and depth to the trade union movement, including support for the campaigns of more trade unions," said Cavalier.
Julie Blackburn, Whittles client partner, added that her firm took the decision to merge as a way to consolidate its commitment to its clients.
"The combined firm of Thompsons will lead with the highest standards and widest range of legal services, providing even greater resources and access from offices covering the whole of the UK," said Blackburn.
The merger will see two of Whittles' three equity partners - Blackburn and Chris Strogen - will join Thompsons partnership, while David Towler will work as a consultant.
Whittles, which was founded almost 100 years ago, has 110 staff altogether, compared to Thompsons which has more than 1,000.